Wednesday 13 August 2014

Option D2: Antacids

D.2.1 State and explain how excess acidity in the stomach can be reduced by the use of different bases

The stomach is unusual in that it generates a pH as low as 1-2 by production of hydrochloric acid from structures in the lining of the walls, known as gastric glands. However, some factors, such as excess alcohol, smoking, stress and some anti-inflammatory drugs, can cause excess prdocution of this acidic secretion known as gastric juice.


Drugs to help combat such excess acid are known as antacids. They work by neutralizing the hydrochloric acid, hence relieving the symptoms. According to the dictum "no acid, no ucler", they do allow the stomach lining time to mend.

Aluminium hydroxide, magnesium hydroxide, sodium hydrogencarbonate and calcium carbonate are prime antacids that are used.



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