Wednesday 13 August 2014

Option D10: Mind-altering drugs

D.10.1 Describe the effects of lysergic acid diethylamide (LSD), mescaline, psilocybin and tetrahydrocannabinol

LSD

  • Potent hallucinogen that creates distortions of the body and crawling geometric patterns
  • Causes impaired judgement, hypertension, dilated pupils and changes to body temperature and heart rate
  • Can cause unpredictable mood swings from euphoria to depression and panic
Mescaline
  • About 1000-3000 times less potent than LSD; causes subjective hallucinations dependent on the individual
  • Effects include anxiety, static tremors, and psychic disturbances with vivid hallucinations
  • Abdominal pain, nausea and diarrhoea are also common.
Psilocybin
  • Produces subjective hallucinations similar to mescaline but milder
  • Some people experience a pleasant mood, others become apprehensive
  • Compulsive movement and inappropriate laughter may occur; also vertigo and dizziness
  • Numbness, muscle weakness and drowsiness are also common
Tetrahydrocannabinol (THC)
  • It acts to depress the central nervous system and cause mental relaxation and euphoria
  • Can lead to loss of inhibitions and an alteration of the perception of time and space
  • Gives a loss of concentration, light-headedness, weakness and a sense of floating are commonly experienced
  • Can cause depression of respiration and can lead to collapse 


D.10.2 Discuss the structural similarities and differences between LSD, mescaline and psilocybin

LSD

  • Benzene ring
  • Alkene
  • Secondary amine
  • Tertiary amine
  • Tertiary amide


Mescaline
  • Benzene ring
  • Primary amine
  • Ether


Psilocybin
  • Benzene ring
  • Secondary amine
  • Tertiary amine ion
  • Phosphate



D.10.3 Discuss the arguments for and against the legalization of cannabis


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